Pancreatic
cancer is the 4th most common cause of cancer-related deaths worldwide.
Regardless of the availability of therapeutic options, the overall 5-year
survival for patients diagnosed with pancreatic cancer remains less than 5%.
Gum resins from Boswellia species, also known as frankincense, have been used
as a major ingredient in Ayurvedic and Chinese medicine to treat a variety of
health-related conditions. The latest research found, both frankincense
chemical extracts and essential oil prepared from Boswellia species gum resins
exhibit anti-neoplastic activity, and have been investigated as potential
anti-cancer agents. The goals of this study are to identify optimal condition
for preparing frankincense essential oil that possesses potent anti-tumor activity,
and to evaluate the activity in both cultured human pancreatic cancer cells and
a xenograft mouse cancer model. Link to article click here
In tstudy, Frankincense was hydro distilled (water process) in 4 different batches at his increasing times or temperatures. 78 degrees C at 2 hours, 10 hours, 12
hours, and the fourth at 100 C for 12 hours. Then, tests were run on pancreatic
cancer cells 24 hours after treatment with frankincense essential oil. These
tests were performed on male mice between 4-5 weeks old that had pancreatic
tumor cells implanted. These tumors were allowed to grow for 7 days. After this
they were given either a control saline solution or Frankincense essential oil
every 4 days
Results:
Frankincense
essential oil increased cytotoxicity (growth suppression) of pancreatic cancer
tumors 3 hours after treatment
Frankincense
essential oil activated apoptosis (cell suicide) in the pancreatic cancer
cells. Tumors began to shrink after the 8th day of treatment
Tumors were
significantly smaller when treated with Frankincense than the control group
(76.67 mm^3 compared to 204 mm^3)
Frankincense
has been tested as an anticancer agent for its ability to turn off the DNA of
cancer cells and return the DNA to a healthy state. Frankincense oil has also
been found to regenerate disc, cartilage, and bone. Therapeutic-grade
frankincense oil contains boswellic acids, which are potent
anti-inflammatory agents against rheumatoid arthritis and osteoporosis
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